Welcome to Quanteon
Vascularised Multi Organ Architecture
Vascularised Multi Organ Architecture
Vascularised Multi Organ Architecture
- The platform integrates liver, bone marrow, and tumour compartments through a continuous endothelial network that enables physiologically relevant circulation. Drugs and metabolites flow between tissues in defined ratios, allowing direct observation of downstream effects such as marrow suppression, immune activation, or tumour response.
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- The platform integrates liver, bone marrow, and tumour compartments through a continuous endothelial network that enables physiologically relevant circulation. Drugs and metabolites flow between tissues in defined ratios, allowing direct observation of downstream effects such as marrow suppression, immune activation, or tumour response.
- This architecture enables coordinated measurement of functional changes across organs rather than isolated endpoints. It directly addresses the inability of existing systems to capture systemic human biology in vitro.
Defined Synthetic Microenvironments
Vascularised Multi Organ Architecture
Vascularised Multi Organ Architecture
- All tissues are supported using fully synthetic extracellular matrices and serum free media. These materials replace animal derived components entirely, removing batch variability and improving reproducibility across experiments.
- The use of defined matrices enables stable long term culture of multiple tissue types within the same fluidic
- All tissues are supported using fully synthetic extracellular matrices and serum free media. These materials replace animal derived components entirely, removing batch variability and improving reproducibility across experiments.
- The use of defined matrices enables stable long term culture of multiple tissue types within the same fluidic circuit. This compatibility is essential for comparative multi organ measurements and regulatory confidence.
PDMS Free Microfluidic Engineering
Vascularised Multi Organ Architecture
PDMS Free Microfluidic Engineering
- The chip is manufactured using PDMS free polymer microfluidics to eliminate small molecule absorption that distorts pharmacokinetic data in silicone based systems. Channel geometry and flow dynamics are optimised to maintain endothelial integrity and physiological shear stress.
- Design for manufacture principles ensure the platform is comp
- The chip is manufactured using PDMS free polymer microfluidics to eliminate small molecule absorption that distorts pharmacokinetic data in silicone based systems. Channel geometry and flow dynamics are optimised to maintain endothelial integrity and physiological shear stress.
- Design for manufacture principles ensure the platform is compatible with scale up, quality control, and routine use in pharmaceutical workflows.